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Hormone Therapy Poses Risk to Women

"The final nail may have been driven into the coffin for the most commonly prescribed combination hormone replacement therapy for women (28th May 2003).  The largest study of HRT to date has found that a woman�s risk of developing dementia, including Alzheimer�s disease, doubles when taking estrogen plus progestin. HRT also failed to protect cognitive function. "

See the Stanford Report's online article at: http://news-service.stanford.edu/news/2003/may28/hrt.html

See lengthy abstracts of two relevant articles at: New article (abstract of it, one has to pay to get full article): http://jama.ama-assn.org/cgi/content/abstract/289/20/2651
Detailed reference:
JAMA. 2003;289:2651-2662 and,
Detailed reference:
JAMA. 2003;289:2663-2672.

Hormone therapy poses risk to women, study says SCIENTISTS FIND HIGH RATES OF CANCER, HEART DISEASE, 9th July 2002.

Scientists today will urge millions of American women taking hormone replacement therapy to avoid its long-term use because of unacceptably high rates of breast cancer and heart disease.

The recommendation comes as researchers halt a massive national study that examined the risks of a combination estrogen-progestin therapy used by an estimated 6 million U.S. women. While the therapy reduced the rate of hip fractures and colon cancer, it created disturbingly higher risks of breast cancer, heart disease, strokes and blood clots in the lungs -- regardless of the women's ethnicity, age or health concerns.
Full report is:
Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women
Principal Results From the Women's Health Initiative Randomized Controlled Trial
Published on the web in the Journal of the American Medical Association Vol. 288 No. 3, July 17, 2002 at http://jama.ama-assn.org/content/vol288/issue3/index.dtl




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Corrine Purcell email: purcell@slac.stanford.edu

Last Updated 03/24/10